Anxiety and depression in patients with multiple sclerosis: The mediating effects of perceived social support.
Identifieur interne : 000670 ( Main/Exploration ); précédent : 000669; suivant : 000671Anxiety and depression in patients with multiple sclerosis: The mediating effects of perceived social support.
Auteurs : Audrey Henry [France] ; Ayman Tourbah [France] ; Gauthier Camus [France] ; Romain Deschamps [France] ; Laurence Mailhan [France] ; Cédric Castex [France] ; Olivier Gout [France] ; Michèle Montreuil [France]Source :
- Multiple sclerosis and related disorders [ 2211-0356 ] ; 2019.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Anxiété (complications), Dépression (complications), Enquêtes et questionnaires (MeSH), Fatigue (complications), Femelle (MeSH), Humains (MeSH), Jeune adulte (MeSH), Mâle (MeSH), Sclérose en plaques (complications), Sclérose en plaques (psychologie), Soutien social (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Échelles d'évaluation en psychiatrie (MeSH).
- MESH :
- psychologie : Sclérose en plaques.
- complications : Adulte, Adulte d'âge moyen, Anxiété, Dépression, Enquêtes et questionnaires, Fatigue, Femelle, Humains, Jeune adulte, Mâle, Sclérose en plaques, Soutien social, Sujet âgé, Sujet âgé de 80 ans ou plus, Échelles d'évaluation en psychiatrie.
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Anxiety (complications), Depression (complications), Fatigue (complications), Female (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Multiple Sclerosis (complications), Multiple Sclerosis (psychology), Psychiatric Status Rating Scales (MeSH), Social Support (MeSH), Surveys and Questionnaires (MeSH), Young Adult (MeSH).
- MESH :
- complications : Anxiety, Depression, Fatigue, Multiple Sclerosis.
- psychology : Multiple Sclerosis.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Social Support, Surveys and Questionnaires, Young Adult.
Abstract
BACKGROUND
Social support has been identified as a buffering or intervening variable in stressful life events. Research has demonstrated that greater social support is associated with better mental health in multiple sclerosis (MS), but little is known about its links to specific aspects of mental health. We therefore investigated if and how perceived social support modulates depression, anxiety and fatigue in patients with MS.
METHODS
We recruited 112 patients with MS from three French hospitals and administered a demographic and clinic interview, and self-report measures of perceived social support (Multidimensional Scale of Perceived Social Support), depression and anxiety (Hospital Anxiety and Depression Scale), and fatigue (Fatigue Severity Scale). We then analyzed the relationships between these domains using path analysis.
RESULTS
The causal path model provided an excellent fit for the data (χ
CONCLUSIONS
This study highlights the important roles played by perceived social support and anxiety in MS. These should be key pharmacological and non-pharmacological targets for optimizing patient care. (NCT 02-880-553).
DOI: 10.1016/j.msard.2018.09.039
PubMed: 30317070
Affiliations:
- France
- Champagne-Ardenne, Grand Est, Île-de-France
- Paris, Reims, Saint-Denis (Seine-Saint-Denis), Versailles
Links toward previous steps (curation, corpus...)
Le document en format XML
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<series><title level="j">Multiple sclerosis and related disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Anxiety (complications)</term>
<term>Depression (complications)</term>
<term>Fatigue (complications)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Multiple Sclerosis (complications)</term>
<term>Multiple Sclerosis (psychology)</term>
<term>Psychiatric Status Rating Scales (MeSH)</term>
<term>Social Support (MeSH)</term>
<term>Surveys and Questionnaires (MeSH)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Anxiété (complications)</term>
<term>Dépression (complications)</term>
<term>Enquêtes et questionnaires (MeSH)</term>
<term>Fatigue (complications)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Sclérose en plaques (complications)</term>
<term>Sclérose en plaques (psychologie)</term>
<term>Soutien social (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Échelles d'évaluation en psychiatrie (MeSH)</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Anxiety</term>
<term>Depression</term>
<term>Fatigue</term>
<term>Multiple Sclerosis</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Sclérose en plaques</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Multiple Sclerosis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Psychiatric Status Rating Scales</term>
<term>Social Support</term>
<term>Surveys and Questionnaires</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anxiété</term>
<term>Dépression</term>
<term>Enquêtes et questionnaires</term>
<term>Fatigue</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Sclérose en plaques</term>
<term>Soutien social</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Échelles d'évaluation en psychiatrie</term>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Social support has been identified as a buffering or intervening variable in stressful life events. Research has demonstrated that greater social support is associated with better mental health in multiple sclerosis (MS), but little is known about its links to specific aspects of mental health. We therefore investigated if and how perceived social support modulates depression, anxiety and fatigue in patients with MS.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>We recruited 112 patients with MS from three French hospitals and administered a demographic and clinic interview, and self-report measures of perceived social support (Multidimensional Scale of Perceived Social Support), depression and anxiety (Hospital Anxiety and Depression Scale), and fatigue (Fatigue Severity Scale). We then analyzed the relationships between these domains using path analysis.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>The causal path model provided an excellent fit for the data (χ</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>This study highlights the important roles played by perceived social support and anxiety in MS. These should be key pharmacological and non-pharmacological targets for optimizing patient care. (NCT 02-880-553).</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30317070</PMID>
<DateCompleted><Year>2019</Year>
<Month>04</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>04</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2211-0356</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>27</Volume>
<PubDate><Year>2019</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Multiple sclerosis and related disorders</Title>
<ISOAbbreviation>Mult Scler Relat Disord</ISOAbbreviation>
</Journal>
<ArticleTitle>Anxiety and depression in patients with multiple sclerosis: The mediating effects of perceived social support.</ArticleTitle>
<Pagination><MedlinePgn>46-51</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S2211-0348(18)30362-6</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.msard.2018.09.039</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Social support has been identified as a buffering or intervening variable in stressful life events. Research has demonstrated that greater social support is associated with better mental health in multiple sclerosis (MS), but little is known about its links to specific aspects of mental health. We therefore investigated if and how perceived social support modulates depression, anxiety and fatigue in patients with MS.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We recruited 112 patients with MS from three French hospitals and administered a demographic and clinic interview, and self-report measures of perceived social support (Multidimensional Scale of Perceived Social Support), depression and anxiety (Hospital Anxiety and Depression Scale), and fatigue (Fatigue Severity Scale). We then analyzed the relationships between these domains using path analysis.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The causal path model provided an excellent fit for the data (χ<sup>2</sup>
= 9.8, p = .778, standardized root mean square residual = 0.043, comparative fit index = 1.00). Results indicated that the level of social support from friends is a predictor of anxiety symptomatology. Thus, anxiety may have both a direct and an indirect impact on fatigue and depression levels.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This study highlights the important roles played by perceived social support and anxiety in MS. These should be key pharmacological and non-pharmacological targets for optimizing patient care. (NCT 02-880-553).</AbstractText>
<CopyrightInformation>Copyright © 2018 Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Henry</LastName>
<ForeName>Audrey</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Cognition, Health and Society Laboratory, University of Reims Champagne-Ardenne, B.P. 30, 57 Rue Pierre Taittinger, 51571 Reims Cedex, France; Psychopathology and Neuropsychology Laboratory, University of Paris 8, 2 rue de la liberté, 93526 Saint-Denis, France. Electronic address: audrey.henry@univ-reims.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tourbah</LastName>
<ForeName>Ayman</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Psychopathology and Neuropsychology Laboratory, University of Paris 8, 2 rue de la liberté, 93526 Saint-Denis, France; Reims University Hospital and Reims Faculty of Medicine, University of Reims Champagne-Ardenne, Reims, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Camus</LastName>
<ForeName>Gauthier</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Cognition, Health and Society Laboratory, University of Reims Champagne-Ardenne, B.P. 30, 57 Rue Pierre Taittinger, 51571 Reims Cedex, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Deschamps</LastName>
<ForeName>Romain</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Adolphe de Rothschild Ophthalmology Foundation, 29 rue Manin, 75019 Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mailhan</LastName>
<ForeName>Laurence</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Porte Verte Hospital, Boulevard de la Porte Verte, 78000 Versailles, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Castex</LastName>
<ForeName>Cédric</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Reims University Hospital and Reims Faculty of Medicine, University of Reims Champagne-Ardenne, Reims, France. Electronic address: ccastex@chu-reims.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gout</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Adolphe de Rothschild Ophthalmology Foundation, 29 rue Manin, 75019 Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Montreuil</LastName>
<ForeName>Michèle</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Psychopathology and Neuropsychology Laboratory, University of Paris 8, 2 rue de la liberté, 93526 Saint-Denis, France.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>10</Month>
<Day>02</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>Mult Scler Relat Disord</MedlineTA>
<NlmUniqueID>101580247</NlmUniqueID>
<ISSNLinking>2211-0348</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
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<MeshHeading><DescriptorName UI="D001007" MajorTopicYN="Y">Anxiety</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
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<MeshHeading><DescriptorName UI="D003863" MajorTopicYN="Y">Depression</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005221" MajorTopicYN="N">Fatigue</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D009103" MajorTopicYN="N">Multiple Sclerosis</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011569" MajorTopicYN="N">Psychiatric Status Rating Scales</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012944" MajorTopicYN="Y">Social Support</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName>
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<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Anxiety</Keyword>
<Keyword MajorTopicYN="N">Depression</Keyword>
<Keyword MajorTopicYN="N">Multiple sclerosis</Keyword>
<Keyword MajorTopicYN="N">Perceived social support</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>07</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2018</Year>
<Month>08</Month>
<Day>11</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>09</Month>
<Day>30</Day>
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<PubMedPubDate PubStatus="pubmed"><Year>2018</Year>
<Month>10</Month>
<Day>15</Day>
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<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>4</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>10</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">30317070</ArticleId>
<ArticleId IdType="pii">S2211-0348(18)30362-6</ArticleId>
<ArticleId IdType="doi">10.1016/j.msard.2018.09.039</ArticleId>
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<affiliations><list><country><li>France</li>
</country>
<region><li>Champagne-Ardenne</li>
<li>Grand Est</li>
<li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
<li>Reims</li>
<li>Saint-Denis (Seine-Saint-Denis)</li>
<li>Versailles</li>
</settlement>
</list>
<tree><country name="France"><region name="Île-de-France"><name sortKey="Henry, Audrey" sort="Henry, Audrey" uniqKey="Henry A" first="Audrey" last="Henry">Audrey Henry</name>
</region>
<name sortKey="Camus, Gauthier" sort="Camus, Gauthier" uniqKey="Camus G" first="Gauthier" last="Camus">Gauthier Camus</name>
<name sortKey="Castex, Cedric" sort="Castex, Cedric" uniqKey="Castex C" first="Cédric" last="Castex">Cédric Castex</name>
<name sortKey="Deschamps, Romain" sort="Deschamps, Romain" uniqKey="Deschamps R" first="Romain" last="Deschamps">Romain Deschamps</name>
<name sortKey="Gout, Olivier" sort="Gout, Olivier" uniqKey="Gout O" first="Olivier" last="Gout">Olivier Gout</name>
<name sortKey="Mailhan, Laurence" sort="Mailhan, Laurence" uniqKey="Mailhan L" first="Laurence" last="Mailhan">Laurence Mailhan</name>
<name sortKey="Montreuil, Michele" sort="Montreuil, Michele" uniqKey="Montreuil M" first="Michèle" last="Montreuil">Michèle Montreuil</name>
<name sortKey="Tourbah, Ayman" sort="Tourbah, Ayman" uniqKey="Tourbah A" first="Ayman" last="Tourbah">Ayman Tourbah</name>
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